UC Santa Cruz Aging and Neurodegeneration Cluster
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Kinesin-1 tail autoregulation and microtubule-binding regions function in saltatory transport but not ooplasmic streamin...

Moua, Pangkong Fullerton, Donna Serbus, Laura R Warrior, Rahul Saxton, William M

Published in Development (Cambridge, England)

DEPS-1 promotes P-granule assembly and RNA interference in C. elegans germ cells.

Spike, Caroline A Bader, Jason Reinke, Valerie Strome, Susan

Published in Development (Cambridge, England)

P granules are germ-cell-specific cytoplasmic structures containing RNA and protein, and required for proper germ cell development in C. elegans. PGL-1 and GLH-1 were previously identified as critical components of P granules. We have identified a new P-granule-associated protein, DEPS-1, the loss of which disrupts P-granule structure and function....

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